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  • Genetic Mechanism behind Inflammatory Bowel Disease Discovered

    Scientists at Children's Hospital of Philadelphia (CHOP) say they have pinpointed a genetic variation responsible for driving the development of inflammatory bowel disease (IBD). The genetic pathway associated with this variation is involved in other immune disorders, suggesting t…

  • Researchers Move Closer to Industrial Production of Heparin in Cell Culture

    Scientists at the University of California-San Diego say they have moved one step closer to the ability to make heparin in cultured cells. Heparin is a potent anti-coagulant and the most prescribed drug in hospitals, yet cell-culture-based production of heparin is currently not po…

  • Grafted Stems Cells Repair Stroke Damaged Brains in Rats

    Repairing neurological damage has never been an easy task for scientists and physicians but remains the ultimate goal for much of the research in neuroscience. For instance, transplanting neuronal stem cells into damaged or diseased areas of the brain has been touted as a potentia…

  • New Tools for Studying Genetic Variation in Cancer

    In cancer genomics, researchers are "really missing a lot of things by not looking for them in the right way," says Shruti Iyer, a PhD candidate in the Genetics Program at Stony Brook University. In a recent talk in New York*, Iyer, who is pursuing her doctoral research in Dr. W. …

  • CRISPR-Cas9 Defies PAM Restrictions, Edits Genomic Regions Once Out of Bounds

    Unless you a re a bacterium, you may want to go PAMless. PAMs, or protospacer adjacent motifs, are what bacteria use to distinguish their own DNA from invasive viral DNA. That is, PAMs help spare bacterial DNA from being cut apart by the bacterial immune system known as CRISPR . P…

  • Breakthrough in unlocking genetic potential of ocean microbes

    Researchers have made a major breakthrough in developing gene-editing tools to improve our understanding of one of the most important ocean microbes on the planet. The international project unlocks the potential of the largest untapped genetic resource for the development of natur…

  • New genetic editing powers discovered in squid

    Revealing yet another super-power in the skillful squid, scientists have discovered that squid massively edit their own genetic instructions not only within the nucleus of their neurons, but also within the axon -- the long, slender neural projections that transmit electrical impu…

  • Gene therapy reverses heart failure in mouse model of Barth syndrome

    Barth syndrome is a rare genetic disease in boys that can cause life-threatening heart failure and also weakens the skeletal muscles and the immune system. There is no specific treatment, but new research, involving new mouse models, shows the potential of a gene therapy approach …

  • Research breakthrough: Humans are not the first to repurpose CRISPR

    We humans are far from the first to exploit the benefits of CRISPR. Groundbreaking research has helped to redefine what CRISPR is. Researchers have discovered that primitive bacterial parasites weaponize CRISPR to engage in battle against one another. This discovery opens up the p…


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