Avantor emphasizes the need to address issues of scalability and manufacturability
2020-01-14A research team has reproduced and visualized the earliest developmental steps in human immune cell production in the laboratory and are now set to advance our understanding of childhood diseases like leukemia and autoimmune conditions.
2020-01-13CAR T-cell therapy, a rapidly emerging form of immunotherapy using patients' own cells to treat certain types of cancers, may be a viable treatment option for another life-threatening condition: heart disease. Researchers at Penn Medicine used genetically modified T cells to targe…
2020-01-10Parkinson's disease, Huntington's disease, cystic fibrosis - these and many other fatal hereditary human diseases are genetically transmitted. Many cancers and cardiovascular diseases are also caused by genetic defects. Gene therapy is a promising possibility for the treatment of …
2020-01-09A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro.
2020-01-08Systems biologist Steven Wiley says advancements in two areas—single-cell biology and CRISPR—are poised to transform research.
2020-01-08Introducing either necroptotic cells or an enzyme that triggers necroptosis can wipe out cancer.
2020-01-07The Zika virus has affected over 60 million people, mostly in South America. It has potentially devastating consequences for pregnant women and their unborn children, many of whom are born with severe microcephaly and other developmental and neurological abnormalities. There is cu…
2020-01-03Questions and Answers about CRISPR Q: What is “CRISPR”? A: “CRISPR” (pronounced “crisper”) stands for Clustered Regularly Interspaced Short Palindromic Repeats, which are the hallmark of a bacterial defense system that forms the basis for CRISPR-Cas9 genome editi…
2020-01-02