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  • Nanoparticles used to deliver CRISPR gene editing tools into the cell

    Researchers from Tufts University and the Chinese Academy of Sciences have developed a novel method to effectively deliver the CRISPR/Cas9 (clustered regularly interspaced short palindromic repeat (CRISPR) associated protein 9) gene editing tools into the liver for genetic studies…

  • Genome editing strategy opens new perspectives in the treatment of cystic fibrosis

    The approach adopted by the team of the University of Trento, led by Anna Cereseto, opens new perspectives in the treatment of cystic fibrosis, a genetic disease for which no cure is currently available. The research work was carried out in collaboration with KU Leuven, in Belgium…

  • Research team redefines the footprint of viral vector gene therapy

    Building on a track record of developing adeno-associated viral (AAV) vectors as a groundbreaking clinical tool for gene therapy and gene editing, researchers report a more sensitive method for capturing the footprint of AAV vectors -- a broad range of sites where the vectors tran…

  • Revolutionizing the CRISPR method

    Researchers have refined the famous CRISPR-Cas method. Now, for the very first time, it is possible to modify dozens, if not hundreds, of genes in a cell simultaneously.

  • Researchers identify new transmembrane protein as chloride ion channel

    In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems. Special channels in the cell membrane selectively permit salt ions to flow in and out of cells. A research team led by Professor Thomas Jentsch at the FMP and MDC has…

  • UC San Diego researchers win $9 million funding to identify cellular cause of type 1 diabetes

    University of California San Diego School of Medicine researchers have been awarded nearly $9 million to fund two multi-institutional research projects that use human pluripotent stem cells, CRISPR and human organoids to dissect beta cell defects and create a human cell model of t…

  • Targeting a blood stem cell subset shows lasting, therapeutically relevant gene editing

    Researchers have used CRISPR-Cas9 to edit long-lived blood stem cells to reverse the clinical symptoms observed with several blood disorders, including sickle cell disease and beta-thalassemia.

  • Fish preserve DNA 'memories' far better than humans do

    We are all familiar with the common myth that fish have poor memory, but it turns that their DNA has the capacity to hold much more memory than that of humans. Rwesearchers report that memory in the form of 'DNA methylation' is preserved between generations of fish, in contrast to…

  • Scientists Develop Modular Approach to Engineering Immune Cells

    Yale researchers have developed a new way to efficiently engineer immune cells, an advance which enhances the ability to fend off cancer and other diseases, they report in the Feb. 25 issue of the journal Nature Methods. A number of new life-saving therapies rely on reconfiguring …


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