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Up to now,there have plenty of publications about the research results of breast cancer using CRISPR technology,and here are some examples.Ubigene successfully constructed a Knockout Cell Line Bank with nearly 2000 genes which could help to facilitate the treatment of breast can…
Yong Chen et al. from Shenzhen People's Hospital found that HAPLN1 accelerated the proliferation of RA-FLSs but inhibited its migration ability. Ubigene constructed HAPLN1 overexpression lentivirus for infection of RA-FLSs to help to study HAPLN1 network.
This study reveals the regulatory role of small nucleolar RNA SNORD17 and p53 pathway in hepatocellular carcinoma, which provides a new potential target for the treatment of hepatocellular carcinoma.Ubigene provided SNORD17 knockout Hep G2 cell line in this study.
In this study,the researchers constructed a radioiodinated RBD as a molecule-targeted probe to non-invasively explore ACE2 expression in vivo,and to investigate radiotherapy pathway for inhibiting ACE2.Ubigene provided ACE2 overexpression HepG2 and HeLa cell lines to verify the af…
Tumor suppressor p53 plays a key role in cellular stress response. p53 is mainly used as a transcription factor to activate or inhibit the transcription of a variety of downstream target genes. Ubigene could offer in-stock KO cell line like p53 knockout cell lines to facilitate th…