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CRISPR library 101 (Part 2) - how to select and construct a CRISPR library? Whole genome CRISPR library or sub library? Loss of function or gain of function? Negative screening or positive screening? CRISPR library is such a good method for gene screening, but how to select and us…
CRISPR library 101 (Part 2) - how to select and construct a CRISPR library? Whole genome CRISPR library or sub library? Loss of function or gain of function? Negative screening or positive screening? CRISPR library is such a good method for gene screening, but how to select and us…
CRISPR library 101 (Part I) - what are the popular applications of CRISPR library? The CRISPR library is the most popular high-throughput screening tool. In this article , Ubigene will give you a brief introduction of this high-throughput screening method from two aspects: what th…
mTOR may have high research value in disease treatment and drug development-Then CRISPR/Cas9 can help! M ammalian target of rapamycin , mTOR is a serine/threonine - protein kinase that is a member of the PIKK protein family and, upon activation by a variety of stimuli, mediates do…
Potential strategy for RA prevention:reduced DNA fragment accumulation by upregulating TREX1 Background Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease with poorly understood pathogenesis. Several factors such as age, smoking history, poor body mass index …