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CRISPR Gene Editing
Stable Overexpression
Stable Interference

IF = 64.8

Nature

Deep whole-genome analysis of 494 hepatocellular carcinomas.

Interpretation

Lei Chen, Chong Zhang, Ruidong Xue, Mo Liu, Jian Bai, Jinxia Bao, Yin Wang, Nanhai Jiang, Zhixuan Li, Wenwen Wang, Ruiru Wang, Bo Zheng, Airong Yang, Ji Hu, Ke Liu, Siyun Shen, Yangqianwen Zhang, Mixue Bai, Yan Wang, Yanjing Zhu, Shuai Yang, Qiang Gao, Jin Gu, Dong Gao, Xin Wei Wang, Hidewaki Nakagawa, Ning Zhang, Lin Wu, Steven G. Rozen, Fan Bai & Hongyang Wang

DOI: 10.1038/s41586-024-07054-3

Related Service or Product: Knockout Cell Lines

IF = 32.4

Immunity

Polyamine metabolism controls B-to-Z DNA transition to orchestrate DNA sensor cGAS activity

Interpretation

Chunyuan Zhao, Yunjin Ma, Minghui Zhang, Xiaoyan Gao, Wenbo Liang, Ying Qin, Yue Fu, Mutian Jia, Hui Song, Chengjiang Gao, Wei Zhao

DOI: 10.1016/j.immuni.2023.09.012

Related Service or Product: Knockout Cell Lines

IF = 27.7

Cell Metabolism

Nondigestible stachyose binds membranous HSP90β on small intestinal epithelium to regulate the exosomal miRNAs: A new function and mechanism

Yueyue Liu, ∙ Tianchi Duan, ∙ Chao Guo ∙ Bin Liu ∙ Xiuqiong Fu ∙ Lu Wang ∙ Xiaoyuan Wang ∙ Xinyue Dong ∙ Chennan Wang ∙ Yalong Lu ∙ Yu Wang ∙ Lin Shi ∙ Honglei Tian ∙ Xingbin Yang

DOI: 10.1016/j.cmet.2024.10.012

Related Service or Product: Knockout Cell Lines

IF = 26.8

Journal of Hepatology

Nuclear miR-204-3p mitigates metabolic dysfunction-associated steatotic liver disease in mice

Zhaowei Zou, Xiu Liu, Jie Yu, Tao Ban, Ziyi Zhang, Peiqi Wang, Renli Huang, Fuxin Zheng, Yafei Chang, Wanli Peng, Yubo Tang, Xiaoqing Feng, Ziying Zhao, Xiaofei Lv, Shuai Huang, Jiawei Guo, Yonghua Tuo, Zhijun Zhou, Sijia Liang

DOI: 10.1016/j.jhep.2024.01.029

Related Service or Product: Knockout Cell Lines

IF = 20.8

Nature Metabolism

Acetate reprogrammes tumour metabolism and promotes PD-L1 expression and immune evasion by upregulating c-Myc

Interpretation

Juhong Wang, Yannan Yang, Fei Shao, Ying Meng, Dong Guo, Jie He & Zhimin Lu

DOI: 10.1038/s42255-024-01037-4

Related Service or Product: Point MutationCas9 Stable Cell Lines

IF = 18.9

Bioactive Materials

Targeted chemotherapy via HER2-based chimeric antigen receptor (CAR) engineered T-cell membrane coated polymeric nanoparticles.

Serkan Yaman, Harish Ramachandramoorthy, Priyanka Iyer, Uday Chintapul, Tam Nguyen, Manoj Sabnani, Tanviben Kotadia, Soroush Ghaffari, Laurentiu M. Pop, Raquibul Hannan, Jon A. Weidanz, Kytai T. Nguyen

DOI: 10.1016/j.bioactmat.2023.12.027

Related Service or Product: Knockout Cell Lines
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