PIH1D1 Knockout cell line (NCI-H82)
Red cotton OmniCell bank
Overview
CRISPR knockout cell lines are engineered through targeted genome editing to eliminate gene function, supporting studies of cellular biology, disease mechanisms, and drug discovery.
PIH1D1 (PIH1 domain containing 1) encodes a protein involved in protein complex assembly and signal transduction. It functions as an enzyme-, histone-, and phosphoprotein-binding factor and is a component of the R2TP complex, RPAP3/R2TP/prefoldin-like complex, and pre-snoRNP complex. PIH1D1 is localized in the cytoplasm and nucleolus, where it contributes to the organization and regulation of macromolecular complexes and associated cellular processes.
Comprehensive quality control includes STR authentication, sterility testing (bacteria and fungi), and mycoplasma screening to ensure purity and performance. Genotype is confirmed by two rounds of PCR and Sanger sequencing, and complete validation reports are provided for make-to-order products.
Product Overview
Key Advantages
Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations
These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.
Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.
Quality Control Specifications
Download STR ReportIntended use
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use
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