
Gene knockout cell lines are genetically engineered using CRISPR-Cas9 technology to precisely disrupt target genes at the genomic level, resulting in complete loss of gene function. These cell models are widely used in gene function studies, signaling pathway analysis, disease mechanism research, and drug target validation. Ubigene has developed a portfolio of over 8,000 gene knockout cell lines, covering major cell types and high-interest targets, enabling rapid support for diverse research needs.
is generated by targeted disruption of the gene in cells. This cell line is designed to facilitate investigation of function in cellular processes, gene regulation, and its involvement in disease-related pathways.The gene knockout cell is validated by Sanger sequencing, and each clone is accompanied by STR authentication documentation. The product is delivered as a homozygous single-cell clone with stable passaging capability. It is guaranteed to be mycoplasma-free and exhibits high viability. In addition, comprehensive technical support and complimentary cell culture guidance are provided throughout use.

Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations
These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.
Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use


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