ZC3HAV1 Knockout cell line (HEK293-A)
Red cotton OmniCell bank
Overview
CRISPR knockout cell lines are engineered through targeted genome editing to eliminate gene function, supporting studies of cellular biology, disease mechanisms, and drug discovery.
ZC3HAV1 (zinc finger CCCH-type containing, antiviral 1) encodes a CCCH-type zinc finger protein that contributes to innate antiviral defense. It promotes degradation of viral mRNAs by recruiting cellular RNA degradation machinery, thereby restricting replication of multiple DNA and RNA viruses. ZC3HAV1 links RNA metabolism with antiviral innate immune responses and provides a cellular mechanism for recognition and elimination of viral transcripts.
Before delivery, each clone is authenticated by STR, tested for sterility and mycoplasma, and genotype‑verified by two‑round PCR‑sequencing. Comprehensive QC data accompany every shipment to support reproducible research.
Product Overview
Key Advantages
Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations
These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.
Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.
Quality Control Specifications
Targeted knockout region: EExon 1
Reference Transcript: NM_020119
Frameshift Mutation Strategy
Download STR ReportIntended use
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use
References
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