ZFP36L2 Knockout cell line (HEK293-A)
Red cotton OmniCell bank
Overview
Ubigene gene knockout cell lines mediated by optimized CRISPR-Cas9 technology provide reliable in vitro models for investigating gene function, signaling pathways, disease mechanisms, and therapeutic targets.
ZFP36L2 (ZFP36 like 2 zinc finger CCCH-type) encodes a member of the TIS11 family containing a characteristic CCCH-type zinc finger domain. It is proposed to function in regulation of cellular responses to growth factors and other extracellular stimuli, although its precise molecular mechanisms remain incompletely characterized. ZFP36L2 is relevant to studies of zinc finger protein function, gene-expression regulation, growth-factor responses, and cellular signaling.
Before delivery, each clone is authenticated by STR, tested for sterility and mycoplasma, and genotype‑verified by two‑round PCR‑sequencing. Comprehensive QC data accompany every shipment to support reproducible research.
Product Overview
Key Advantages
Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations
These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.
Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.
Quality Control Specifications
Targeted knockout region: EExon 2
Reference Transcript: NM_006887
Frameshift Mutation Strategy
Download STR ReportIntended use
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use
References
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