ZFP69B Knockout cell line (HEK293-A)
Red cotton OmniCell bank
Overview
Gene knockout cell lines are generated using CRISPR-Cas9 based technology to precisely disrupt target genes, enabling functional genomics research, disease modeling, and target validation.
ZFP69B (ZFP69 zinc finger protein B) encodes a zinc finger protein predicted to function as an RNA polymerase II-specific transcription factor and to bind transcriptional regulatory DNA sequences. It is involved in Golgi organization and localizes to the nucleolus. These properties suggest potential roles in transcriptional regulation and cellular organization, although the molecular mechanisms connecting ZFP69B to Golgi function remain incompletely characterized.
Comprehensive quality control includes STR authentication, sterility testing (bacteria and fungi), and mycoplasma screening to ensure purity and performance. Genotype is confirmed by two rounds of PCR and Sanger sequencing, and complete validation reports are provided for make-to-order products.
Product Overview
Key Advantages
Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations
These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.
Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.
Quality Control Specifications
Targeted knockout region: EExon 3
Reference Transcript: NM_001369565
Frameshift Mutation Strategy
Download STR ReportIntended use
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use
References
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