ZNF587B Knockout cell line (HEK293-A)
Red cotton OmniCell bank
Overview
Gene knockout cell lines are generated using CRISPR-Cas9 based technology to precisely disrupt target genes, enabling functional genomics research, disease modeling, and target validation.
ZNF587B (zinc finger protein 587B) encodes a zinc finger protein predicted to function as a sequence-specific transcription factor involved in regulation of RNA polymerase II-dependent transcription. The protein is predicted to bind DNA regulatory regions and to function in the nucleus. These characteristics suggest a potential role in gene expression regulation, although the specific transcriptional targets and biological processes controlled by ZNF587B remain incompletely characterized.
Before delivery, each clone is authenticated by STR, tested for sterility and mycoplasma, and genotype‑verified by two‑round PCR‑sequencing. Comprehensive QC data accompany every shipment to support reproducible research.
Product Overview
Key Advantages
Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations
These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.
Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.
Quality Control Specifications
Targeted knockout region: EExon 3
Reference Transcript: NM_001204818
Frameshift Mutation Strategy
Download STR ReportIntended use
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use
References
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