ZNF81 Knockout cell line (HEK293-A)
Red cotton OmniCell bank
Overview
CRISPR knockout cell lines are engineered through targeted genome editing to eliminate gene function, supporting studies of cellular biology, disease mechanisms, and drug discovery.
ZNF81 (zinc finger protein 81) encodes a zinc finger protein containing an N-terminal KRAB domain and several C2H2-type zinc finger motifs. These domains are characteristic of transcriptional regulators involved in DNA binding and gene expression control. ZNF81 likely functions as a transcription factor, although its specific molecular targets and regulatory functions remain incompletely characterized.
Each knockout cell line is validated by STR authentication, sterility testing (bacteria/fungi), and mycoplasma screening. Genotype is confirmed by two rounds of PCR and Sanger sequencing. Only clones that pass all QC criteria are released, ensuring reliable identity and performance for downstream applications.
Product Overview
Key Advantages
Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations
These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.
Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.
Quality Control Specifications
Targeted knockout region: EExon 3
Reference Transcript: NM_007137
Frameshift Mutation Strategy
Download STR ReportIntended use
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use
References
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