ZSCAN21 Knockout cell line (NCI-H82)
Red cotton OmniCell bank
Overview
CRISPR knockout cell lines are engineered through targeted genome editing to eliminate gene function, supporting studies of cellular biology, disease mechanisms, and drug discovery.
ZSCAN21 (zinc finger and SCAN domain containing 21) encodes a zinc finger protein with predicted sequence-specific DNA-binding transcription activator activity. It is involved in positive regulation of RNA polymerase II-dependent transcription and is predicted to function in the nucleus. Through its DNA-binding and transcriptional regulatory activities, ZSCAN21 may contribute to control of gene expression, although the specific target genes and biological pathways regulated by this protein remain incompletely characterized.
Comprehensive quality control includes STR authentication, sterility testing (bacteria and fungi), and mycoplasma screening to ensure purity and performance. Genotype is confirmed by two rounds of PCR and Sanger sequencing, and complete validation reports are provided for make-to-order products.
Product Overview
Key Advantages
Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations
These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.
Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.
Quality Control Specifications
Targeted knockout region: EExon 2
Reference Transcript: NM_001362781
Frameshift Mutation Strategy
Download STR ReportIntended use
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use
References
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