CLDN18 Stable Expression Cell Line (PANC-1)
Red cotton OmniCell bank
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use. | Sample Name | hCLDN18-1CтMean | β-h_actinCтMean | ΔCтMean | ΔΔCт | Expression Rate |
|---|---|---|---|---|---|
| CLDN18 Stable Expression Cell Line (PANC-1) | 20.105 | 14.599 | 5.506 | -12.913 | 7712.592 |
| PANC-1_Ctrl(Puro) | 34.153 | 15.734 | 18.419 | 0.000 | 1.000 |
Intended use
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use
Unpacking and Storage Instructions
Handling procedure
Product Advantage
Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations
These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.
Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.
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