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CLDN6 Stable Expression Cell Line (MC38)

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CLDN6 Stable Expression Cell Line (MC38)
Size
1*10^6
Culture method
90% DMEM+10%FBS
Instruction
-
STR Report
Detailed Product Information
CLDN6 Stable Expression Cell Line (MC38)

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.

Product category
Stable Cell Lines
Transcript
NM_021195.5
Cell Name
CLDN6 Stable Expression Cell Line (MC38)
Species
Human
Gene Name
CLDN6
Passage ratio
1:2-1:4
Cell Morphology
Epithelial-like, Mixed: adherent and suspensio
Antibiotic Concentration
-
Culture method
90% DMEM+10%FBS
Mycoplasma test
negative
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.

Intended use

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use

Product Advantage

Easy to use
Easy to use

Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations

High-efficient KO
High-efficient KO

These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.

Curated cells
Curated cells

Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.

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