
The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.
| Sample Name | CYP11B2-2CтMean | Q-CHOK1CтMean | ΔCтMean | ΔΔCт | Expression Rate |
|---|---|---|---|---|---|
| CYP11B2 Stable Expression Cell Line (V79) | 24.908 | 19.168 | 5.740 | -9.349 | 652.123 |
| V79_Ctrl(Puro) | 35.384 | 20.295 | 15.089 | 0.000 | 1.000 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use
Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations
These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.
Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.


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