
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
| Sample Name | hIL6-1CтMean | β-h_actinCтMean | ΔCтMean | ΔΔCт | Expression Rate |
|---|---|---|---|---|---|
| IL6 Stable Expression Cell Line (HEK293) | 13.758 | 15.188 | -1.430 | -17.203 | 150875.602 |
| HEK293_Ctrl(Puro) | 30.681 | 14.908 | 15.773 | 0.000 | 1.000 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use
Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations
These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.
Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.





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