
This gene encodes a member of the kallikrein subfamily of serine proteases that are involved in diverse physiological functions such as skin desquamation, tooth enamel formation, seminal liquefaction, synaptic neural plasticity and brain function. The encoded preproprotein undergoes proteolytic cleavage of the activation peptide to generate the functional enzyme. Mice lacking the encoded protein are unable to generate significant levels of kinins in most tissues, develop cardiovascular abnormalities and exhibit hypercalciuria of renal origin. This gene is located in a cluster of several related kallikrein genes on chromosome 7. Alternative splicing results in multiple transcript variants encoding different isoforms, some of which may undergo similar processing.
| Sample Name | mKlk1-1CтMean | Q-mGAPDHCтMean | ΔCтMean | ΔΔCт | Expression Rate |
|---|---|---|---|---|---|
| Klk1 Stable Expression Cell Line (RAW 264.7) | 23.03 | 15.19 | 7.840 | -14.573 | 24373.064 |
| RAW264.7_Ctrl(Puro) | 38.422 | 16.009 | 22.413 | 0.000 | 1.000 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use
Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations
These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.
Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.





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