MICA Stable Expression Cell Line (MC38-Luc)
Red cotton OmniCell bank
downloadThis gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use. | Sample Name | hMICA-1CтMean | Q-mGAPDHCтMean | ΔCтMean | ΔΔCт | Expression Rate |
|---|---|---|---|---|---|
| MICA Stable Expression Cell Line (MC38-Luc) | 19.887 | 13.229 | 6.658 | -15.681 | 52535.318 |
| MC38-Luc_Ctrl(Hygro) | 35.098 | 12.759 | 22.339 | 0.000 | 1.000 |
Intended use
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use
Unpacking and Storage Instructions
Handling procedure
Product Advantage
Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations
These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.
Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.
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