
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
| Sample Name | hNAE1-1CтMean | β-h_actinCтMean | ΔCтMean | ΔΔCт | Expression Rate |
|---|---|---|---|---|---|
| NAE1 Stable Expression Cell Line (HuH-7) | 16.467 | 15.863 | 0.604 | -3.898 | 14.908 |
| Huh-7_Ctrl(Puro) | 19.015 | 14.513 | 4.502 | 0.000 | 1.000 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use
Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations
These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.
Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.










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