
SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control.
| Sample Name | SIRT3CтMean | h_actin-3CтMean | ΔCтMean | ΔΔCт | Expression Rate |
|---|---|---|---|---|---|
| SIRT3 Stable Expression Cell Line (NCI-H716) | 19.522 | 15.285 | 4.237 | -5.340 | 40.504 |
| NCI-H716_Ctrl(Puro) | 25.978 | 16.401 | 9.577 | 0.000 | 1.000 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use
Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations
These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.
Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.



Simply fill out the form below to leave your inquiry
— we will respond within 24 Hours.
* Name
* Institution
* Products & Services of Interest
If email is not available, how else can we reach you?
How did you hear about us?