Vinculin Stable Expression Cell Line (THP-1)
Red cotton OmniCell bank
downloadVinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use. | Sample Name | Vinculin-1CтMean | β-h_actinCтMean | ΔCтMean | ΔΔCт | Expression Rate |
|---|---|---|---|---|---|
| Vinculin Stable Expression Cell Line (THP-1) | 22.035 | 13.276 | 8.759 | -4.025 | 16.280 |
| THP-1_Ctrl(Puro) | 25.637 | 12.853 | 12.784 | 0.000 | 1.000 |
Intended use
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use
Unpacking and Storage Instructions
Handling procedure
Product Advantage
Cas9 cell lines in our cell bank can stably express Cas9 protein. Each Cas9 Stable Cell Line is easy to use and enables gene knockout simply by transfecting gRNA, while transfection of gRNA and donor DNA results in gene knock-in or point mutations
These Cas9 stable cell lines have been used to construct the KO cell lines for various genes, gene KO efficiency 5-10 times improved.
Selected cells, low passages, good cell condition, high activity, applicable for all kinds of gene-editing experiments.
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