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CRISPR-U™ knockout cell line, is more efficient than traditional gene-editing methods. With CRISPR-U™, Ubigene has successfully knockout more than 100 cell lines.
2021-06-23
Ubigene uses CRISPR-U™ knockdown cell line. The knockdown vector would be transferred into the cells by lentivirus transduction. After drug screening, WT cells die out and a positive cell pool obtained.
2021-06-23Gene overexpression cell line: the overexpression vector would be transferred into the cells by lentivirus transduction or piggyBac transposition. After drug screening, WT cells die out and a positive cell pool obtained.
2021-06-23CRISPR-U™ gene knockin cell line increases the efficiency to 10X than traditional gene knockin methods. With CRISPR-U™, Ubigene has successfully gene knockin more than 100 cell lines.
2021-06-23CRISPR-U™ gene point mutation cell line: The cells would be co-transfected with gRNA, Cas9 and donor oligo by electroporation, and then screened. After drug screening, single clones would be generated. Positive clones would be validated by sequencing.
2021-06-23
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