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How to utilize CRISPR in drug discover (Part 3 )--ion channel Ion channel is a hydrophilic protein microporous channel composed of transmembrane proteins on the cell membrane, which can regulate the difference of ion concentration inside and outside the membrane, and then regulate…
New idea for pancreatic cancer therapy - targeting USP8 enhances PD-L1 immunotherapy sensitivity! PD-L1 , o ne ligand for P rogrammed death receptor 1 (PD-1), is a key voucher for T cell to recognize “ enemy ” and “ our side ” . Normally, T cells avoid killing their tissue…
SNP research needs point mutation cells - Summary of 4 constructionmethods | Ubigene Uncover the secret of the point mutationcell construction method Well-researched 4 methods of point mutationconstruction assist with SNP research With the rapid development of NGS, more and more h…
ncRNA isclosely relating to disease, so how can we study its function? The sequencingresults of the human genome show that there are more than 20,000 genesresponsible for encoding proteins, accounting for less than 2% of the total genomelength. Many protozoa also have more than 20…
They used the differentiation potential of human embryonic stem cells to establish the NLGN3 R451C point mutation neuron model through CRISPR/Cas9 gene editing technology.