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  • Knockout iPSC Cell line

    Many serious diseases cannot be cured by medicines, such as heart failure, Late Stage Diabetes, hemophilia, myeloma, End-Stage Cirrhosis, etc. The best method is allogeneic transplantation. However, due to the limited donors and the risk of immune rejection, researchers are dedica…

  • THP-1 Cell Line Gene-editing

    A human leukemic cell line (THP-1) cultured from the blood of a boy with acute monocytic leukemia. Since its establishment in 1980, THP-1 cells have been widely used in the research of monocyte and macrophage related mechanisms, signaling pathways, nutrient and drug transportation…

  • CircRNA Knockout Cell line

    circRNAs are circular noncoding RNAs formed by reverse splicing of pre-mRNAs. circRNAs were firstly found in viruses in the 1970s. However, due to the extensive use of the method for enrichment of poly (A) (no 5 'and 3' ends of circRNA) in the early RNA library preparation, …

  • Gene-Editing Salmonella: an ideal vector for tumor-targeting therapy

    Salmonella is a facultative anaerobic gram-negative rod-shaped bacteria. Salmonella belongs to Enterobacteriaceae and is an important medical pathogen of human and animal. In China, food poisoning caused by Salmonella accounts for 40% of bacterial food poisoning incidents. Salmone…

  • [Frontier Research] New method of spinal cord injury treatment

    Spinal cord injury (SCI) causes primary mechanical injury and secondary inflammation-mediated injury. Mechanical injury of spinal cord tissue causes primary injury, and secondary neuroinflammatory reaction occurs after primary injury, which mediates additional extensive nerve inju…


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