Gene Knockdown (RNA Interference) Cell Line Service

Gene knockdown cell lines are generated by introducing shRNA interference vectors into cells via lentiviral transduction. Cells are then subjected to drug selection based on an optimized concentration until all control cells are eliminated, resulting in stable gene-silenced cell lines. Final delivery includes cell pools or single clones along with associated data reports. This service is applicable to a variety of research areas, including cancer mechanism studies, signal transduction, and drug target validation.

Why choose Ubigene？

Broad Cell Type Coverage

Compatible with cancer cell lines and normal cell types, suitable for a wide range of experimental models.

Standardized Deliverables

Delivery is available in cell pool or single-clone formats, accompanied by a comprehensive data report.

Extensive Experience

Over 300 successful gene editing projects delivered, providing stable and reliable knockdown cell lines.

Comprehensive Quality Control

Multi-dimensional validation, including RT-qPCR, ensures accurate gene overexpression or knockdown efficiency.

Knockdown (RNA Interference) Cell Line Service

Cell type

Various types of cells including tumor cell lines, regular cell lines

Deliverables

Cell pool/Single-cell clone

Turnaround

Please Inquire

Price

Start from $1780

*For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.

300+ Successful Gene-editing Cell Line Types

Digestive System

Human Gallbladder Carcinoma Cell Line (GBC-SD)Human Hepatoma Cell Line (Hep G2)Human Hepatoma Cell Line (SNU-387)Human Hepatoma Cell Line (HuH-7)Human Hepatoma Cell Line (SK-HEP-1)Human Hepatoma Cell Line (Hep 3B)Human Normal Hepatocytes Cell line (L-02)Human Colon Cancer Cell Line (HCT 116)Human Colon Cancer Cell Line (HT-29)Human colorectal adenocarcinoma Cell Line (RKO)Human colorectal adenocarcinoma Cell Line (Caco-2)Human Esophageal Squamous Carcinoma Cell Line (KYSE-150)Human gastric cancer Cell Line (AGS)Mouse Hepatocarcinoma Cell Line (Hepa 1-6)Murine colorectal carcinoma Cell Line (CT26.WT)Murine colorectal carcinoma Cell Line (MC38)Human Esophageal Squamous Carcinoma Cell Line (KYSE-30)Mouse Hepatocarcinoma Cell Line (H22)Human Gastric Cancer Cell Line (NCI-N87)Human colorectal adenocarcinoma Cell Line (SW480)Human Hepatoma Cell Line (SMMC-7721)Porcine intestinal epithelial Cell Line (IPEC-J2)Human Gastric Cancer Cell Line (HGC-27)Human Gastric Cancer Cell Line (MGC-803)Human renal carcinoma cell line (ACHN)Human colorectal adenocarcinoma Cell Line (LS 174T)Immortalized Human Hepatic Cell Line (C3A)Human Hepatoma Cell Line (PLC/PRF/5)Human colorectal adenocarcinoma Cell Line (SW 48)Human colorectal adenocarcinoma Cell Line (SW948)Human colorectal adenocarcinoma Cell Line (NCI-H716)Mouse hepatocyte Cell Line (AML12)Human Gastric Cancer Cell Line (SGC-7901)Human Ileocecal Cancer Cell Line (HRT-18)Human Colon Cancer Cell Line (LoVo)Human Hepatoma Cell Line (MHCC97-H)Human Gastric Cancer Cell Line (MKN-45)Human Colon Cancer Cell Line (COLO 205)Rat Liver Cell Line (BRL)Mouse Gastric Cancer Cell Line (MFC)Human Colon Cancer Cell Line (SW620)Human Hepatoma Cell Line (Li-7)Mouse Ascites Sarcoma Cell Line (S180)Rat Liver Cell Line (BRL-3A)Human Colon Cancer Cell Line (HCT-15)Human Gastric Cancer Cell Line (KATO III)Human colorectal adenocarcinoma Cell Line (SW1463)Human Gastric Cancer Cell Line (SNU-5)Human colorectal adenocarcinoma Cell Line (SW1116 [SW 1116, SW-1116])Human Hepatic Stellate Cell Line (LX-2)Human Hepatoma Cell Line (HCCLM3)

Endocrine System

Human Submandibular Gland Epidermoid Carcinoma Cell Line (A-253)Human Mammary Epithelial Cell Line (MCF 10A)Human Breast Cancer Cell Line (MDA-MB-231)Human Breast Cancer Cell Line (MCF7)Human Breast Cancer Cell Line (MDA-MB-415)Human Breast Cancer Cell Line (MDA-MB-468)Human Breast Epithelial Cell Line Integrating SV40 Gene (HBL-100)Human Prostate Cancer Cell Line (LNCaP Clone FGC)Human Prostate Cancer Cell Line (PC-3)Human Prostate Cancer Cell Line (22RV1)Human pancreatic cancer Cell Line (BxPC-3)Mouse Breast Cancer Cell Line (4T1)Mouse Acinar Pancreatic Cell Line (266-6)Human Breast Cancer Cell Line (JIMT-1)Mouse prostate cancer Cell Line (RM-1)Human Breast Cancer Cell Line (SK-BR-3)Human Breast Cancer Cell Line (HCC1806)Human Thyroid Normal Cell Line (Nthy-ori 3-1)Mouse pancreatic cancer Cell Line (Pan-02)Human Pancreatic Carcinoma Cell Line (SW1990)Human acute lymphoblastic leukemia Cell Line (MOLT4)Human Pancreatic Carcinoma Cell Line (Panc-1)Mouse Breast Adenocarcinoma Cell Line (E0771)Human Thyroid Squamous Cell Carcinoma Cell line (SW579)Human Breast Cancer Cell Line (HCC1143)Human breast cancer Cell Line (BT-549)Human acute lymphoblastic leukemia Cell Line (MT-4)Py230 Cell Line (Py230)Human Thyroid Cancer Cell Line (TPC-1)Human Prostate Cancer Cell Line (PC-3M)Human Burkitt's Lymphoma Cell Line(RAJI)Human Metastatic Pancreatic Adenocarcinoma Cell Line (AsPC-1)Human NK Leukemia Cell Line (YT)Human Prostate Cancer Cell Line (DU145)Mouse Mammary Epithelial Cell Line (HC11)Mouse Breast Cancer Cell Line (C127)Human Thyroid Normal Cell Line (Nthy-ori 3-1)Human Pancreatic Carcinoma Cell Line (MIA PaCa-2)Mouse Breast Cancer Cell Line (EMT6)Human Prostate Cancer Cell Line (VCaP)Human Breast Cancer Cell Line (SUM-149PT)Human breast ductal cancer cell Line (BT474)Human Pancreatic Carcinoma Cell Line (Capan2)

Respiratory System

Human Lung Cancer Cell Line (A549)Human Lung Cancer Cell Line (NCI-H1299)Human Lung Cancer Cell Line (NCI-H520)Human Lung Cancer Cell Line (SK-MES-1)Mouse Lewis lung carcinoma Cell Line (LLC)Human Bronchial Epithelial Cell Line (BEAS-2B)Human Lung Cancer Cell Line (HCC827)Porcine alveolar macrophage cell line (3D4/21)Human lung adenocarcinoma Cell Line (PC9)Human Lung Cancer Cell Line (NCI-H1650)Human Lung Cancer Cell Line (NCI-H727)Human lung adenocarcinoma Cell Line (NCI-H1975)Human lung cancer Cell Line (NCI-H292)Human Lung Cancer Cell Line (NCI-H23)Human Lung Cancer Cell Line (MSTO-211H)Human Lung Cancer Cell Line (NCI-H358)Human Non-small Cell Lung Carcinoma Cell Line (NCI-H460)Human lung adenocarcinoma Cell Line (Calu-3)Human Fetal Lung Fibroblast Cell Line (MRC-5)Human Highly Metastatic Lung Cancer Cell Line (95-D)Human Colon Carcinoma Cell Line (T84)MLE-12 Cell Complete Medium (MLE-12)Human Fetal Lung Fibroblast Cell Line (WI-38)Human Lung Cancer Cell Line (DMS114))Human lung adenocarcinoma Cell Line (NCI-H1373)Human Lung Cancer Cell Line (NCI-H1703)Human Lung Cancer Cell Line (DMS 53)Human Small Cell Lung Cancer Cell Line (NCI-H82 [H82])Human Small Cell Lung Cancer Cell Line (SHP-77)Human Lung Cancer Cell Line (NCI-H2170)

Reproductive System

Human Amniotic Cell Line (WISH)Human Highly Metastatic Ovarian Cancer Cell Line (HO-8910PM)African green monkey kidney Cell Line (Marc-145)Human Cervical Carcinoma Cell Line (Hela)Human ovarian cancer Cell Line (OVCAR-3)Human Ovarian Adenocarcinoma Cell Line (Caov-3)Mouse Embryonic Fibroblasts (NIH/3T3)Mouse Fibroblast Cell Line (TM3)Human Villous Trophoblast (HTR-8/SVneo)Human Ovarian Granulosa Cell Line (KGN)Chinese Hamster Ovary Cell Line (CHO-K1)Human Endometrial Adenocarcinoma Cell Line (MFE-280)Mouse ovarian epithelial cancer Cell (ID8)Human endometrial adenocarcinoma Cell (HEC-1-B)Human Endometrial Carcinoma Cell Line (ISHIKAWA)Human Cervical Carcinoma Cell Line (C-33 A)Human Cervical Carcinoma Cell Line (Ca Ski)Human Endometrial Carcinoma Cell Line (KLE)Mouse Teratocarcinoma Cell Line (P19)Human Ovarian Clear Cell Carcinoma Cell Line (ES-2)Human Endometrial Adenocarcinoma Cell Line (AN3 CA)Human Cervical Carcinoma Cell Line (hela 229)Human Ovarian Adenocarcinoma Cell Line (SK-OV-3)Human Choriocarcinoma Cell Line (Bewo)

Circulatory System

Rat Cardiac Myocytes (H9c2(2-1))Mouse Myoblast Cell Line (C2C12)Human Cardiac Myocytes (AC16)Mouse Aortic Smooth Muscle Cell Line (MOVAS)

Blood and lymphatic System

Mouse Hybridoma Cell Line (AE-1)Hybridoma (Anti-Cd3) Cell Line (OKT 3)Human Monocytic Cell Line (THP-1)Human Histiocytic Lymphoma Cell Line (U-937)Human T Lymphocyte Cell Line (Jurkat, Clone E6-1)Human Acute Lymphocyte Cell Line (OCI-Aml-3)Human myelogenous Leukemia Cell Line (K-562)Mouse Macrophage Cell Line (RAW 264.7)Human Acute Promyelocytic Leukemia Cell Line (HL-60)Human B Lymphoma Cell Line (U-2932)Mouse B Lymphoma Cell Line (A20)Human Myelomonocytic Leukemia Cell Line (MV4-11)Human B Lymphoma Cell Line (SU-DHL-4)Human Acute Myeloid Leukemia Cell Line (KG-1a)Human Erythroleukemia Cell Line (HEL)Mouse Pro B Cell Line (BAF3)Human acute promyelocytic leukemia cell line (NB4)Human T-lymphocyte Cell Line (Hut-78)Human B Lymphocytes Cell Line (GM12878)Mouse Lymphoma Cell Line (EL4)Mouse Macrophage Cell Line (Ana-1)Human Erythroleukemia Cell Line (TF-1)Human Lymphoma Cell Line (BC-3)Human Multiple Myeloma Peripheral Blood B Lymphocytes (RPMI 8226)Human Burkitt's Lymphoma B Lymphocytes (Ramos)Human B lymphoma cell line (SU-DHL-6)Human Acute Lymphoblastic Leukemia Cell Line (Non-B Non-T)(Reh)Human Acute Lymphocyte Cell Line (Kasumi-1)Human Mantle Cell Lymphoma Cell Line (JeKo-1)Human peripheral blood mantle lymphoma Cell Line (Mino)Human Acute Myeloid Leukemia Cell Line (MOLM13)Human B lymphocytic leukaemia Cell Line (NALM-6)Human B lymphoma Cell Line (SU-DHL-8)

Brain and Nervous System

Rat Glioblastoma Cell Line (C6)Mouse Hippocampal Neuronal Cell Line (HT-22)Human Neuroblastoma Cell Line (SK-N-SH)Human Neuroblastoma Cell Line (SH-SY5Y)Human glioblastoma Cell Line (U-87 MG)Human glioblastoma Cell Line (U251MG)Mouse Anterior Parietal Bone Cell Line (MC3T3-E1 Subclone 14)Mouse microglia Cell Line (BV2)Human microglial clone 3 Cell Line (HMC3)Mouse neuroblastoma Cell Line (Neuro-2a)Human glioblastoma Cell Line (LN-229)Mouse Glioblastoma Cell Line (GL261)Human Glioblastoma Cell Line (T98G)Human Glioblastoma Cell Line (A-172)Human Neuroblastoma Cell Line (SK-N-BE(2))Human Brain Astrocytoma Cell Line (Hs 683)Rat Glioblastoma Cell Line (RG2)

Urinary System

African green monkey kidney Cell (Vero)African green monkey kidney Cell (VERO C1008 (E6))Dog Kidney Cell Line (MDCK(NBL-2))Human Embryonic Kidney Cell Line (293T)Human Embryonic Kidney Cell Line (293T)Human Embryonic Kidney Cell Line (HEK293)Rat adrenal pheochromocytoma Cell Line (Low differentiation)(PC-12)Human Bladder Transitional Cell Carcinoma Cell Line (T24)Human bladder carcinoma cell line (5637)Mouse Bladder Cancer Cell (MB-49)Human renal cell carcinoma Cell Line (786-0)Human renal cell carcinoma Cell Line(MS751)Mouse podocyte Cell Line(MPC-5)Pig Kidney Cell line(PK-15)Human Embryonic Kidney Cell Line (2V6.11)Human Bladder Transitional Cell Carcinoma Cell Line (SW780)Transformed (SV40) African Green Monkey Kidney Cell Line (COS-1)Transformed (SV40) African Green Monkey Kidney Cell Line (COS-7)Rat Kidney Cell Line (NRK-52E)Mouse Renal Adenocarcinoma Cell Line (RenCa)Bovine Kidney (MDBK) Cell Line (MDBK (NBL-1))Hamster Kidney Fibroblasts (BHK-21)Human Renal Proximal Tubular Epithelial Cell Line (HK-2)Human Urinary Bladder Squamous Cell Carcinoma Cell Line (SCaBER)Mouse Renal Adenocarcinoma Cell Line (RAG)Mouse Bladder Cancer Cell (MBT-2)Human renal carcinoma Cell Line (OS-RC-2)

Skeleton, Articulus, Soft Tissue, Derma System

Human Umbilical Vein Cell Line (EA.hy926)Mouse Lewis lung carcinoma Cell Line (U-2 OS)Human Osteosarcoma Cell Line (Saos-2)Human skin squamous carcinoma Cell Line (A-431)Murine melanoma Cell Line (B16-F10)Human malignant melanoma Cell Line (A-375)Human Skin Fibroblast Cell Line (BJ)Mouse Fibroblast Cell Line (L-929)Mouse Lewis lung carcinoma Cell Line (SW 1353)Human fibrosarcoma Cell Line (HT-1080)Rat osteosarcoma Cell Line(UMR-106)Human Immortalized Keratinocytes Cell Line (HaCaT)Chicken Fibroblast Cell Line (DF1)Human Multiple Myeloma Cell Line (MM.1S)Human Corneal Epithelial Cell Line (HCE-T)(HCE-T)Immortalized Human Lens Epithelial Adherent Cell Line (SRA01/04)Mouse Lewis lung carcinoma Cell Line (MG-63)Mouse Osteosarcoma Cell Line (K7M2-WT)Mouse Lewis lung carcinoma Cell Line (143B)Mouse Subcutaneous Connective Tissue Cell Line (A9)Mouse squamous carcinoma Cell Line (SCC-7)Human Choriocarcinoma Cell Line (JAR)Human bone osteosarcoma epithelial Cell Line (KHOS-240S)Mouse Chondrogenic Cell Line (ATDC5)

Stem Cell Lines

Human induced pluripotent stem cells (iPSC) (IPSC-DYR0100)

Ocular, Otolaryngologic and Oral System

Human Pharyngeal Carcinoma Cell Line (Pleural Effusion Metastasis) (Detroit 562)Human retinal pigment epithelial Cell Line (ARPE-19)Human Nasopharyngeal Carcinoma Cell Line (CNE1)Human oral squamous carcinoma Cell Line (HSC3)Human nasopharyngeal carcinoma Cell Line (HK-1)Human oral squamous carcinoma cell line (CAL-27)Mouse Cochlear Hair Cell Line (HEI-OC1)Human Retinoblastoma Cell Line (Y79)Human Tongue Squamous Carcinoma Cell Line (SCC-9)Human Pharyngeal Squamous Cell Carcinoma Cell Line (FaDu)

Digestive System